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Design and synthesis of pyrimidine-5-carbonitrile hybrids as COX-2 inhibitors: Anti-inflammatory activity, ulcerogenic liability, histopathological and docking studies

Medicinal ChemistryCox-2 InhibitorsMedicineDrug DiscoveryPharmacological AgentPyrimidine-5-carbonitrile HybridsPharmacotherapyUlcerogenic LiabilityAnti-cancer AgentDrug DevelopmentPharmacologyBiomolecular Engineering