Studies on the constituents of solanaceous plants. Part XXIV. Three New Withanolides, Physagulins E, F and G from Physalis angulata L..

Abstract

Three new withanolides, physagulins E(1), F(2), and G(3) were isolated from the fresh berries of Physalis angulate L. (Solanaceae). Their structures were established as (20S, 22R)-15α-acetoxy-5α, 6β, 14α, 28-tetrahydroxy-1-oxowitha-2, 16, 24-trienolide-28-O-D-glucopyranoside (1), (20R, 22R)-15α-acetoxy-16β, 17β-epoxy-5α, 6β-14β-trihydroxy-1-oxo-witha-2, 24-dienolide (2) and (20R, 22R)-15α-acetoxy-16β, 17β-epoxy-5α, 6β, 14β, 28-tetrahydroxy-1-oxo-witha-2, 24-dienolide 28-O-β-D-dlucopyranoside (3) by spectroscopic means.