Antimicrobial and antioxidant chlorinated azaphilones from mangrove <i>Diaporthe perseae</i> sp. isolated from the stem of Chinese mangrove <i>Pongamia pinnata</i>

Abstract

Many plants remain unexplored for their endophytic fungi that may possess potentially important phytochemicals. Consequently, we have focused to discover new natural products from endophytic fungus <i>Diaporthe perseae</i> sp. isolated from the stem of the Chinese mangrove <i>Pongamia pinnata (L.)</i> Pierre plant that led to the isolation of one new chlorinated <i>isochromophilone G</i> (<b>1</b>) along with six known azaphilones (<b>2-7</b>). The structures of the isolated compounds were elucidated by UV, NMR and Mass spectroscopic analysis. All the isolated compounds were screened for their antimicrobial and anti-oxidant activities.