Concepedia

A Small Molecule that Binds an RNA Repeat Expansion Stimulates Its Decay via the Exosome Complex

Alicia J. Angelbello, Raphael I. Benhamou, Suzanne G. Rzuczek, Shruti Choudhary, Zhenzhi Tang, Jonathan L. Chen, Madhuparna Roy, Kye Won Wang, Ilyas Yildirim, Albert S. Jun,

Cell chemical biology · 2020 · 47 citations · 53 references

Open access

Concepts

Life SciencesCell BiologyMolecular BiologyRna ProcessingRna DecayRna StructureRna TurnoverRna-binding ProteinsRna-protein InteractionsExoribonuclease-mediated Rna DecayExosome-mediated Rna DecayExosome-mediated Rna DegradationRna Binding Proteins In DecayRna Exosome RegulationRna Exosome-mediated Decay

References

53

UCSF Chimera—A visualization system for exploratory research and analysis

Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang et al. · Journal of Computational Chemistry · 2004 · 47.8K citations

Computing, Bioinformatics, Visualization +17

The Protein Data Bank

Helen M. Berman · Nucleic Acids Research · 2000 · 39.8K citations

Life Sciences, Biochemistry, Bioinformatics +10

Development and testing of a general amber force field

Junmei Wang, Romain M. Wolf, James W. Caldwell et al. · Journal of Computational Chemistry · 2004 · 19.6K citations

Natural Sciences, Biophysics, Chemistry +17

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

Wendy D. Cornell, Piotr Cieplak, Christopher I. Bayly et al. · Journal of the American Chemical Society · 1995 · 13.1K citations

Natural Sciences, Biochemistry, Biophysics +17

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +16