Inhibition of histamine receptor H3 suppresses the growth and metastasis of human non-small cell lung cancer cells via inhibiting PI3K/Akt/mTOR and MEK/ERK signaling pathways and blocking EMT

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Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction

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High constitutive activity of native H3 receptors regulates histamine neurons in brain

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Clinical responses to EGFR-tyrosine kinase inhibitor retreatment in non-small cell lung cancer patients who benefited from prior effective gefitinib therapy: a retrospective analysis

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