Concepedia

Downregulation of FOXO6 alleviates hypoxia-induced apoptosis and oxidative stress in cardiomyocytes by enhancing Nrf2 activation via upregulation of SIRT6

Aiping Jin, Qianrong Zhang, Shulin Li, Bing Li

Journal of Bioenergetics and Biomembranes · 2020 · 22 citations · 21 references

DOI

Concepts

References

21

Heart Disease and Stroke Statistics—2020 Update: A Report From the American Heart Association

Salim S. Virani, Álvaro Alonso, Emelia J. Benjamin et al. · Circulation · 2020 · 9.4K citations · Full text

, , +17

SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2

Huize Pan, Di Guan, Xiaomeng Liu et al. · Cell Research · 2016 · 337 citations · Full text

, , +17

SIRT6 protects cardiomyocytes against ischemia/reperfusion injury by augmenting FoxO3α-dependent antioxidant defense mechanisms

Xiao-Xiao Wang, Xu-Lei Wang, Ming-ming Tong et al. · Basic Research in Cardiology · 2016 · 155 citations

, , +14

Sirtuin 6 protects the brain from cerebral ischemia/reperfusion injury through NRF2 activation

Wei Zhang, Rui Wei, Zhang Lin et al. · Neuroscience · 2017 · 141 citations

, , +16

FoxO6 Integrates Insulin Signaling With Gluconeogenesis in the Liver

Dae Hyun Kim, Germán Perdomo, Ting Zhang et al. · Diabetes · 2011 · 136 citations · Full text

, , +17