Concepedia

Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes

Jingjing Chen, Yalei Li, Jie Zhang, Minmin Zhang, Aihuan Wei, Hong‐Chun Liu, Zhicheng Xie, Wenming Ren, Wenwen Duan, Zhuo Zhang,

European Journal of Medicinal Chemistry · 2020 · 54 citations · 23 references

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References

23

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

Paweł K. Mazur, Alexander Herner, Stephano S. Mello et al. · Nature Medicine · 2015 · 417 citations · Full text

, , +17

Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer

Emily J. Faivre, Keith F. McDaniel, Daniel H. Albert et al. · Nature · 2020 · 404 citations

, , +10

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer

Hanlin Zeng, Jia Qu, Nan Jin et al. · Cancer Cell · 2016 · 165 citations

, , +15

Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non–Small Cell Lung Cancer

Dennis O. Adeegbe, Yan Liu, Patrick H. Lizotte et al. · Cancer Discovery · 2017 · 150 citations · Full text

, , +17

Potent Dual BET/HDAC Inhibitors for Efficient Treatment of Pancreatic Cancer

Shipeng He, Guoqiang Dong, Yu Li et al. · Angewandte Chemie International Edition · 2020 · 149 citations

, , +14