Concepedia

Uric acid drives intestinal barrier dysfunction through TSPO-mediated NLRP3 inflammasome activation

Qiulan Lv, Daxing Xu, Jinfeng Ma, Yan Wang, Xiaomin Yang, Peng Zhao, Liang Ma, Zhiyuan Li, Wan Yang, Xiu Liu,

Inflammation Research · 2020 · 41 citations · 35 references

DOI

Concepts

References

35

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou, Amir S. Yazdi, Philippe Menu et al. · Nature · 2010 · 5.4K citations

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Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

Jorge Henao‐Mejia, Eran Elinav, Chengcheng Jin et al. · Nature · 2012 · 2.4K citations

, , +12

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

Raúl Muñoz-Planillo, Peter Kuffa, Giovanny J. Martínez-Colón et al. · Immunity · 2013 · 2.1K citations

, , +16

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Christoph A. Thaiss, Maayan Levy, Inna Grosheva et al. · Science · 2018 · 914 citations

, , +17

The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3

Moritz M. Gaidt, Thomas S. Ebert, Dhruv Chauhan et al. · Cell · 2017 · 637 citations · Full text

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