Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA

Involvement of the <i>bcl</i> -2 Gene in Human Follicular Lymphoma

Yoshihide Tsujimoto, Jeffrey Cossman, Elaine S. Jaffe et al. · Science · 1985 · 1.8K citations

Life Sciences, Genetics, Molecular Genetics +16

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

David M. Hockenbery, Mary M. Zutter, William F. Hickey et al. · Proceedings of the National Academy of Sciences · 1991 · 1.3K citations

Life Sciences, Cell Biology, Immunology +12

The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition

Brenda L. Bloodgood, Nikhil Sharma, Heidi A. Browne et al. · Nature · 2013 · 324 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +7

Major Groove Binding and ‘DNA-Induced' Fit in the Intercalation of a Derivative of the Mixed Topoisomerase I/II Poison <i>N</i>-(2-(Dimethylamino)ethyl)acridine-4- carboxamide (DACA) into DNA:  X-ray Structure Complexed to d(CG(5-BrU)ACG)₂ at 1.3-Å Resolution

Alan K. Todd, Adrienne Adams, James H. Thorpe et al. · Journal of Medicinal Chemistry · 1999 · 89 citations

Life Sciences, Molecular Biology, Bioisosterism +7

p53, Bax and Bcl-2 expression, and apoptosis in gestational trophoblast of complete hydatidiform mole

Shuang Qiao, T Nagasaka, Toshiyuki Harada et al. · Placenta · 1998 · 76 citations

Life Sciences, Genetics, Molecular Biology +13