Concepedia

Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis

Zhen Cai, Chien‐Feng Li, Fei Han, Chunfang Liu, Anmei Zhang, Che-Chia Hsu, Danni Peng, Xian Zhang, Guoxiang Jin, Abdol-Hossein Rezaeian,

Molecular Cell · 2020 · 268 citations · 37 references

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37

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Sibylle Jäger, Christoph Handschin, Julie St‐Pierre et al. · Proceedings of the National Academy of Sciences · 2007 · 2.4K citations · Full text

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

Yasuhiko Minokoshi, Young‐Bum Kim, Odile D. Peroni et al. · Nature · 2002 · 2K citations

, , +13

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

Seth B. Coffelt, Kelly Kersten, Chris W. Doornebal et al. · Nature · 2015 · 1.7K citations · Full text

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PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

Valerie S. LeBleu, Joyce T. O’Connell, Karina N. Gonzalez Herrera et al. · Nature Cell Biology · 2014 · 1.4K citations · Full text

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Oxidative stress inhibits distant metastasis by human melanoma cells

Elena Piskounova, Michalis Agathocleous, Malea M. Murphy et al. · Nature · 2015 · 1.3K citations

, , +14