Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

Adrienne H. Long, Waleed Haso, Jack F. Shern et al. · Nature Medicine · 2015 · 1.8K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Prevalence of Type 1 and Type 2 Diabetes Among Children and Adolescents From 2001 to 2009

Dana Dabelea, Elizabeth J. Mayer‐Davis, Sharon Saydah et al. · JAMA · 2014 · 1.4K citations

Public Health, Child Health, Pediatrics +10

Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells

Omkar U. Kawalekar, Roddy S. O’Connor, Joseph A. Fraietta et al. · Immunity · 2016 · 1.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

Mark D. Pescovitz, Carla J. Greenbaum, Heidi Krause‐Steinrauf et al. · New England Journal of Medicine · 2009 · 1.1K citations · Full text

Life Sciences, Endocrinology, Immunology +16

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

Jeffrey A. Bluestone, Jane H. Buckner, Mark Fitch et al. · Science Translational Medicine · 2015 · 1K citations

Life Sciences, Endocrinology, Immunology +11