Iron Overload-Induced Osteocyte Apoptosis Stimulates Osteoclast Differentiation Through Increasing Osteocytic RANKL Production In Vitro

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

Tomoki Nakashima, Mikihito Hayashi, Takanobu Fukunaga et al. · Nature Medicine · 2011 · 1.7K citations

Medicine, Cell Biology, Physiology +16

Matrix-embedded cells control osteoclast formation

Jinhu Xiong, Melda Onal, Robert L. Jilka et al. · Nature Medicine · 2011 · 1.3K citations · Full text

Medicine, Cell Biology, Bone Metabolism +11

Osteocyte Apoptosis Is Induced by Weightlessness in Mice and Precedes Osteoclast Recruitment and Bone Loss

J. Ignacio Aguirre, Lilian I. Plotkin, Scott Stewart et al. · Journal of Bone and Mineral Research · 2006 · 489 citations

Medicine, Cell Biology, Physiology +17

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

Kiyo‐aki Ishii, Toshio Fumoto, Kazuhiro Iwaï et al. · Nature Medicine · 2009 · 401 citations

Life Sciences, Cell Biology, Molecular Biology +14

Bcl-2 and Bax function independently to regulate cell death

C. Michael Knudson, Stanley J. Korsmeyer · Nature Genetics · 1997 · 396 citations

Life Sciences, Biochemistry, Cell Biology +11