J. Ignacio Aguirre

Osteocyte Apoptosis Is Induced by Weightlessness in Mice and Precedes Osteoclast Recruitment and Bone Loss

J. Ignacio Aguirre, Lilian I. Plotkin, Scott Stewart et al. · Journal of Bone and Mineral Research · 2006 · 489 citations

Medicine, Cell Biology, Physiology +17

Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs

Lilian I. Plotkin, Irina Mathov, J. Ignacio Aguirre et al. · American Journal of Physiology-Cell Physiology · 2005 · 272 citations

Life Sciences, Cell Biology, Physiology +17

Endothelial Nitric Oxide Synthase Gene-Deficient Mice Demonstrate Marked Retardation in Postnatal Bone Formation, Reduced Bone Volume, and Defects in Osteoblast Maturation and Activity

J. Ignacio Aguirre, Lee Buttery, Meg C. O'Shaughnessy et al. · American Journal Of Pathology · 2001 · 240 citations · Full text

Medicine, Developmental Biology, Bone Metabolism +10

Bisphosphonates and Estrogens Inhibit Osteocyte Apoptosis via Distinct Molecular Mechanisms Downstream of Extracellular Signal-regulated Kinase Activation

Lilian I. Plotkin, J. Ignacio Aguirre, Stavroula Kousteni et al. · Journal of Biological Chemistry · 2004 · 239 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Transient Versus Sustained Phosphorylation and Nuclear Accumulation of ERKs Underlie Anti-Versus Pro-apoptotic Effects of Estrogens

Jin Ran Chen, Lilian I. Plotkin, J. Ignacio Aguirre et al. · Journal of Biological Chemistry · 2004 · 146 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17