Prediction of negative food effect induced by bile micelle binding on oral absorption of hydrophilic cationic drugs

Transit of pharmaceutical dosage forms through the small intestine.

S.S. Davis, John G. Hardy, J W Fara · Gut · 1986 · 848 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure–activity relationship (QSAR) with the Abraham descriptors

Yuan H. Zhao, Joelle Le, Michael H. Abraham et al. · Journal of Pharmaceutical Sciences · 2001 · 521 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Comparison of Canine and Human Gastrointestinal Physiology

Jennifer Dressman · Pharmaceutical Research · 1986 · 332 citations · Full text

Life Sciences, Physiology, Veterinary Physiology +12

Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination

Manthena V. S. Varma, R. Scott Obach, Charles J. Rotter et al. · Journal of Medicinal Chemistry · 2010 · 325 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

IN VITRO P-GLYCOPROTEIN INHIBITION ASSAYS FOR ASSESSMENT OF CLINICAL DRUG INTERACTION POTENTIAL OF NEW DRUG CANDIDATES: A RECOMMENDATION FOR PROBE SUBSTRATES

Jarkko Rautio, Joan E. Humphreys, Lindsey O. Webster et al. · Drug Metabolism and Disposition · 2006 · 261 citations

Medicine, Pharmacokinetics, Pharmacology +17