Concepedia

Oral Absorption Optimization

Oral Absorption Optimization is a pharmacokinetic optimization strategy that specifically enhances the extent and rate of drug uptake across the gastrointestinal membrane into systemic circulation following oral administration.

185

Publications

10.1K

Citations

1.2K

Authors

259

Institutions

Publications per year

2017–2026

60

Parents

Publications

185

Rate-Limited Steps of Human Oral Absorption and QSAR Studies

Yuan H. Zhao, Michael H. Abraham, Joelle Le et al. · Pharmaceutical Research · 2002 · 707 citations

, , +16

Self-emulsifying drug delivery systems (SEDDS) with polyglycolyzed glycerides for improving in vitro dissolution and oral absorption of lipophilic drugs

Nita H. Shah, Micaela Carvajal, Chandresh Patel et al. · International Journal of Pharmaceutics · 1994 · 478 citations

, , +17

Using the Golden Triangle to optimize clearance and oral absorption

Ted W. Johnson, Klaus Dress, Martin P. Edwards · Bioorganic & Medicinal Chemistry Letters · 2009 · 382 citations

, , +14

Combined Use of Crystalline Salt Forms and Precipitation Inhibitors to Improve Oral Absorption of Celecoxib from Solid Oral Formulations

Héctor R. Guzmán, Mark Tawa, Zhong Zhang et al. · Journal of Pharmaceutical Sciences · 2007 · 377 citations

, , +15

Physicochemical Space for Optimum Oral Bioavailability: Contribution of Human Intestinal Absorption and First-Pass Elimination

Manthena V. S. Varma, R. Scott Obach, Charles J. Rotter et al. · Journal of Medicinal Chemistry · 2010 · 325 citations

, , +16

1–5 of 185

Authors

1.2K

  1. KS
    Kiyohiko Sugano

    Ritsumeikan University, Japan

    4 publications · 244 citations

    4

    h-index

  2. SM
    Satoru Matsumoto

    Keio University, Japan

    3 publications · 39 citations

    3

    h-index

  3. KK
    Kohji Kawabata

    Mochida Pharmaceutical (Japan), Japan

    3 publications · 39 citations

    3

    h-index

  4. ST
    Shuichi Tawara

    Mochida Pharmaceutical (Japan), Japan

    3 publications · 39 citations

    3

    h-index

  5. YM
    Yoshimi Matsumoto

    Mochida Pharmaceutical (Japan), Japan

    3 publications · 39 citations

    3

    h-index

1–5 of 1.2K

Institutions

259

  1. Shenyang Pharmaceutical University

    Shenyang, China

    12 h-index

    65 publications

    2.5K citations

  2. Pfizer (United States)

    New York, United States

    7 h-index

    91 publications

    8.5K citations

  3. Chungnam National University

    Daejeon, South Korea

    4 h-index

    16 publications

    726 citations

  4. United States Military Academy

    West Point, United States

    4 h-index

    41 publications

    925 citations

  5. Setsunan University

    Osaka, Japan

    4 h-index

    14 publications

    530 citations

  6. Novartis (Switzerland)

    Basel, Switzerland

    3 h-index

    7 publications

    261 citations

  7. National Institute for Materials Science

    Tsukuba, Japan

    3 h-index

    10 publications

    335 citations

  8. China Pharmaceutical University

    Nanjing, China

    3 h-index

    20 publications

    405 citations

1–8 of 259

Venues

  1. International Journal of Pharmaceutics

    21 publications · 1.6K citations

    18

    h-index

  2. Journal of Pharmaceutical Sciences

    13 publications · 1K citations

    13

    h-index

  3. Journal of Medicinal Chemistry

    11 publications · 885 citations

    11

    h-index

  4. Pharmaceutical Research

    10 publications · 1.1K citations

    10

    h-index

  5. European Journal of Pharmaceutical Sciences

    9 publications · 433 citations

    9

    h-index

1–5