Shinji Sakuma

Site of drug absorption after oral administration: Assessment of membrane permeability and luminal concentration of drugs in each segment of gastrointestinal tract

Yoshie Masaoka, Yusuke Tanaka, Makoto Kataoka et al. · European Journal of Pharmaceutical Sciences · 2006 · 175 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone.

Kenji Iwasaki, Toshifumi Shiraga, Kazuko Nagase et al. · Drug Metabolism and Disposition · 1993 · 106 citations

Life Sciences, Biochemistry, Pharmacology +16

Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506.

Kenji Iwasaki, Toshifumi Shiraga, H Matsuda et al. · Drug Metabolism and Disposition · 1995 · 105 citations

Life Sciences, Biochemistry, Pharmacology +17

Effect of Food Intake on the Oral Absorption of Poorly Water-Soluble Drugs: In Vitro Assessment of Drug Dissolution and Permeation Assay System

Makoto Kataoka, Yoshie Masaoka, Shinji Sakuma et al. · Journal of Pharmaceutical Sciences · 2006 · 102 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Design of novel bioconjugates for targeted drug delivery

Zheng‐Rong Lu, Jane-Guo Shiah, Shinji Sakuma et al. · Journal of Controlled Release · 2002 · 101 citations

Pharmacy, Pharmaceutical Biotechnology, Pharmaceutics +14