Kazuko Nagase

Scheduled infliximab monotherapy to prevent recurrence of Crohnʼs disease following ileocolic or ileal resection: A 3-year prospective randomized open trial

Kōji Yoshida, Ken Fukunaga, Hiroki Ikeuchi et al. · Inflammatory Bowel Diseases · 2011 · 151 citations · Full text

Metabolism of FK506, a potent immunosuppressive agent, by cytochrome P450 3A enzymes in rat, dog and human liver microsomes

Toshipumi Shiraga, Hiroji Matsuda, Kazuko Nagase et al. · Biochemical Pharmacology · 1994 · 130 citations

Cytochrome P450 3A, Biochemistry, Medicine +12

Distribution and Protein Binding of FK506, a Potent Immunosuppressive Macrolide Lactone, in Human Blood and Its Uptake by Erythrocytes

Kazuko Nagase, Kazuhide Iwasaki, Katsuko Nozaki et al. · Journal of Pharmacy and Pharmacology · 1994 · 115 citations

Immunology, Blood Cell, Cell Death +22

Isolation, identification, and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone.

Kenji Iwasaki, Toshifumi Shiraga, Kazuko Nagase et al. · Drug Metabolism and Disposition · 1993 · 106 citations

Further metabolism of FK506 (tacrolimus). Identification and biological activities of the metabolites oxidized at multiple sites of FK506.

Kenji Iwasaki, Toshifumi Shiraga, H Matsuda et al. · Drug Metabolism and Disposition · 1995 · 104 citations