Concepedia

EGFR‐mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions

Chenyao Wang, Xin Wang, Manoj Veleeparambil, Patricia Kessler, Belinda Willard, Saurabh Chattopadhyay, Ganes C. Sen

The EMBO Journal · 2020 · 72 citations · 45 references

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45

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

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STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

Liufu Deng, Hua Liang, Meng Xu et al. · Immunity · 2014 · 2.1K citations · Full text

, , +17

STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

Yasuo Tanaka, Zhijian J. Chen · Science Signaling · 2012 · 1.3K citations · Full text

, , +14

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

Xiang Gui, Hui Yang, Tuo Li et al. · Nature · 2019 · 1.3K citations · Full text

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