CircATP2B4 promotes hypoxia-induced proliferation and migration of pulmonary arterial smooth muscle cells via the miR-223/ATR axis

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

Julia Salzman, Charles Gawad, Peter Lincoln Wang et al. · PLoS ONE · 2012 · 2.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Chk1 is an essential kinase that is regulated by Atr and required for the G₂/M DNA damage checkpoint

Qinghua Liu, Saritha Guntuku, Xian-Shu Cui et al. · Genes & Development · 2000 · 1.6K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death‐dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension

Laimute Taraseviciene‐Stewart, Yasunori Kasahara, Lori Alger et al. · The FASEB Journal · 2001 · 807 citations

Medicine, Pharmacology, Apoptosis +15

Circular RNAs in cancer: novel insights into origins, properties, functions and implications.

Jingqiu Li, Jie Yang, Ping Zhou et al. · PubMed · 2015 · 436 citations

Life Sciences, Molecular Biology, Oncology +17

Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension

M. Sean McMurtry · Journal of Clinical Investigation · 2005 · 365 citations · Full text

Medicine, Cardiology, Molecular Medicine +16