Concepedia

Asenapine and iloperidone decrease the expression of major cytochrome P450 enzymes CYP1A2 and CYP3A4 in human hepatocytes. A significance for drug-drug interactions during combined therapy

Przemysław J. Danek, Jacek Wójcikowski, Władysława A. Daniel

Toxicology and Applied Pharmacology · 2020 · 11 citations · 10 references

DOI

Concepts

References

10

Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins

Helga H.J. Gerets, Karen Tilmant, Brigitte Gerin et al. · Cell Biology and Toxicology · 2012 · 679 citations · Full text

, , +17

Clinical pharmacology of atypical antipsychotics: an update

Montserrat Maurí, Silvia Paletta, M. Maffini et al. · PubMed · 2014 · 250 citations · Full text

, , +14

The Impact of Serious Mental Illness on Health and Healthcare

Mark Viron, Theodore A. Stern · Psychosomatics · 2010 · 205 citations

, , +12

Interactions between the cytochrome P450 system and the second-generation antipsychotics

Trevor I. Prior, Glen B. Baker · Journal of Psychiatry and Neuroscience · 2003 · 185 citations

, , +17

Interindividual Variability in Gene Expression Profiles in Human Hepatocytes and Comparison with HepaRG Cells

Alexandra Rogue, Carine Lambert, Catherine Spire et al. · Drug Metabolism and Disposition · 2011 · 68 citations

, , +17