Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in heparg cells

Sébastien Anthérieu, Alexandra Rogue, Bernard Fromenty, +2

Hepatology

Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver

Alexandra Rogue, Catherine Spire, Manuel Brun, +2

PPAR Research

Fatty Liver DiseaseInsulin SignalingMetabolic SyndromeMolecular PharmacologyHepatotoxicity +21

Comparative Gene Expression Profiles Induced by PPARγ and PPARα/γ Agonists in Human Hepatocytes

Alexandra Rogue, Carine Lambert, Rozenn Jossé, +4

PLoS ONE

Interindividual Variability in Gene Expression Profiles in Human Hepatocytes and Comparison with HepaRG Cells

Alexandra Rogue, Carine Lambert, Catherine Spire, +2

Drug Metabolism and Disposition

PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells

Alexandra Rogue, Sébastien Anthérieu, Aurore Vluggens, +5

Toxicology and Applied Pharmacology

InflammationOxysterolMedicineLiver PhysiologyPharmacology +1

An adaptation of the human HepaRG cells to the in vitro micronucleus assay

Rozenn Jossé, Alexandra Rogue, Elisabeth Lorge, +1

Mutagenesis

Vitro Micronucleus TestBlood CellPathologyImmunophenotypingCell Culture +22

Biodistribution of intravitreal lenadogene nolparvovec gene therapy in nonhuman primates

David J. Calkins, Patrick Yu‐Wai‐Man, Nancy J. Newman, +7

Molecular Therapy — Methods & Clinical Development

Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in rat hepatocytes

Alexandra Rogue, Marie Pierre Renaud, Nancy Claude, +2

Toxicology and Applied Pharmacology

Molecular PharmacologyTranscriptional RegulationPparα/γ AgonistsSignal TransductionMolecular Pathway +10

<i>In Vitro</i>Human Placental Studies to Support Adenovirus-Mediated<i>VEGF-D^ΔNΔC</i>Maternal Gene Therapy for the Treatment of Severe Early-Onset Fetal Growth Restriction

Michelle Desforges, Alexandra Rogue, Nick Pearson, +9

Human Gene Therapy Clinical Development

Biodistribution and predictive hepatic gene expression of intravenous iron sucrose

P.R. Elford, Johanne Bouchard, Léonore Jaillet, +4

Journal of Pharmacological and Toxicological Methods

Intravenous Iron SucroseHepatologyBiochemistryHeme HomeostasisNatural Sciences +11