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Acute depletion of telomerase components DKC1 and NOP10 induces oxidative stress and disrupts ribosomal biogenesis via NPM1 and activation of the P53 pathway

Reductive StressGenome InstabilityTelomerase Components Dkc1Oncogenic AgentMolecular BiologyCellular SenescenceAcute DepletionTumor SuppressorP53 PathwayMedicineCell BiologyOxidative Stress