Chemically modified curcumin (CMC2.24) alleviates osteoarthritis progression by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis via the NF-κB/HIF-2α axis

Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis

Tadashi Hayami, Maureen Pickarski, Ya Zhuo et al. · Bone · 2005 · 627 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development

Taku Saito, Atsushi Fukai, Akihiko Mabuchi et al. · Nature Medicine · 2010 · 545 citations · Full text

Medicine, Genetics, Molecular Biology +17

C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes

Makoto Hirata, Fumitaka Kugimiya, Atsushi Fukai et al. · Human Molecular Genetics · 2011 · 165 citations

Medicine, Molecular Biology, Molecular Genetics +17

Curcumin Inhibits Apoptosis of Chondrocytes through Activation ERK1/2 Signaling Pathways Induced Autophagy

Xiaodong Li, Kai Feng, Li Jiang et al. · Nutrients · 2017 · 139 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Curcumin attenuates inflammatory response in IL-1β-induced human synovial fibroblasts and collagen-induced arthritis in mouse model

Dong‐Oh Moon, Mun-Ok Kim, Yung Hyun Choi et al. · International Immunopharmacology · 2010 · 132 citations

Medicine, Immunology, Pathology +17