Concepedia

Pyruvate Kinase M2 Tetramerization Protects against Hepatic Stellate Cell Activation and Liver Fibrosis

Dandan Zheng, Yuchuan Jiang, Chen Qu, Hui Yuan, Kaishun Hu, Lu He, Peng Chen, Jinying Li, Mengxian Tu, Lehang Lin,

American Journal Of Pathology · 2020 · 83 citations · 39 references

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References

39

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

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Liver cirrhosis

The Lancet · 2008 · 1.9K citations · Full text

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Liver fibrosis

Ramón Bataller · Journal of Clinical Investigation · 2005 · 1.5K citations · Full text

, , +17

Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

Ingmar Mederacke, Christine Hsu, Juliane S. Troeger et al. · Nature Communications · 2013 · 1.4K citations · Full text

, , +12

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel et al. · Cell Metabolism · 2015 · 1.4K citations · Full text

, , +16