Concepedia

Loss of the laminin subunit alpha‐3 induces cell invasion and macrophage infiltration in cutaneous squamous cell carcinoma*

Matthew Caley, Vera Martins, Kate M. Moore, M. Lashari, Liisa Nissinen, Veli‐Matti Kähäri, Stephanie Alexander, Emily P. Jones, Catherine Harwood, Judith K. Jones,

British Journal of Dermatology · 2020 · 13 citations · 38 references

DOIFull text

Open access

Abstract

These data provide evidence that loss of the laminin α3 chain in cSCC has an effect on both the epithelial and immune components of cSCC, resulting in an aggressive tumour microenvironment.

References

38

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

Peter J. Murray, Judith E. Allen, Subhra K. Biswas et al. · Immunity · 2014 · 6K citations · Full text

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Anne E. Carpenter, Thouis R. Jones, Michael R. Lamprecht et al. · Genome biology · 2006 · 5.4K citations · Full text

Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study

Kay Brantsch, Christoph Meisner, Birgitt Schönfisch et al. · The Lancet Oncology · 2008 · 1K citations

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Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

Jonathan B. Mitchem, Donal J. Brennan, Brett L. Knolhoff et al. · Cancer Research · 2012 · 929 citations · Full text

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ROCK- and Myosin-Dependent Matrix Deformation Enables Protease-Independent Tumor-Cell Invasion In Vivo

Jeffrey Wyckoff, Sophie Pinner, Steve Gschmeissner et al. · Current Biology · 2006 · 434 citations · Full text

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