GMM-Demux: sample demultiplexing, multiplet detection, experiment planning, and novel cell-type verification in single cell sequencing

Visualizing Data using t-SNE

Laurens van der Maaten, Geoffrey E. Hinton · Journal of Machine Learning Research · 2008 · 35.7K citations

Engineering, Data Visualization, Data Exploration +16

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler, Paul Hoffman, Peter Smibert et al. · Nature Biotechnology · 2018 · 14.1K citations · Full text

Engineering, Genetics, Multiomics +17

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

Evan Z. Macosko, Anindita Basu, Rahul Satija et al. · Cell · 2015 · 7.6K citations · Full text

Systems Biology, Functional Genomics, Single Cell Sequencing +12

Massively parallel digital transcriptional profiling of single cells

Grace Zheng, Jessica M. Terry, Phillip Belgrader et al. · Nature Communications · 2017 · 7.4K citations · Full text

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

Christopher S. McGinnis, Lyndsay M. Murrow, Zev J. Gartner · Cell Systems · 2019 · 4.2K citations · Full text

Doublet Detection, Functional Genomics, Sequencing +15