Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes

Dries Feyen, Wesley L. McKeithan, Arne A.N. Bruyneel, Sean Spiering, Larissa Hörmann, Bärbel Ulmer, Hui Zhang, Francesca Briganti, Michaela Schweizer, Bence Hegyi,

Cell Reports · 2020 · 405 citations · 45 references

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Abstract

channel SCN5A and dilated cardiomyopathy due to a mutation in the RNA splicing factor RBM20. The maturation media should increase the fidelity of hiPSC-CMs as disease models.

References

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