A programmable sequence of reporters for lineage analysis

A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

Martin Jínek, Krzysztof Chylinski, Ines Fonfara et al. · Science · 2012 · 17.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

Life Sciences, Genetics, Molecular Biology +10

The Tol2kit: A multisite gateway‐based construction kit for <i>Tol2</i> transposon transgenesis constructs

Kristen M. Kwan, E. Fujimoto, Clemens Grabher et al. · Developmental Dynamics · 2007 · 1.9K citations

Life Sciences, Biotechnology, Genetics +15

Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation

John G. Doench, Ella Hartenian, Daniel B. Graham et al. · Nature Biotechnology · 2014 · 1.7K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

Improved Splice Site Detection in Genie

Martin G. Reese, Frank H. Eeckman, David Kulp et al. · Journal of Computational Biology · 1997 · 1.6K citations

Life Sciences, Bioinformatics, Genetics +10