Concepedia

Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation

Roman Sloutsky, Noelle Dziedzic, Matthew J. Dunn, Rachel M. Bates, Ana P. Torres‐Ocampo, Sivakumar Boopathy, Brendan Page, John G. Weeks, Luke H. Chao, Margaret M. Stratton

Science Signaling · 2020 · 57 citations · 44 references

DOIFull text

Open access

Concepts

Abstract

/CaM sensitivity in CaMKII is homolog dependent and includes substantial contributions from the hub domain. Our sequencing approach, combined with biochemistry, provides insights into understanding the complex pool of endogenous CaMKII splice variants.

References

44

UCSF Chimera—A visualization system for exploratory research and analysis

Eric F. Pettersen, Thomas D. Goddard, Conrad C. Huang et al. · Journal of Computational Chemistry · 2004 · 47.8K citations

, , +17

Features and development of <i>Coot</i>

Paul Emsley, Bernhard Lohkamp, W. G. Scott et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 29.6K citations · Full text

, , +16

<i>PHENIX</i>: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 24.5K citations · Full text

, , +16

MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization

Kazutaka Katoh, John Rozewicki, Kazunori Yamada · Briefings in Bioinformatics · 2017 · 9K citations · Full text

, , +14

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

Shawn Zheng, Eugene Palovcak, Jean‐Paul Armache et al. · Nature Methods · 2017 · 8.9K citations · Full text

, , +12