Concepedia

Pharmacokinetics of fosfomycin in patients with prophylactic treatment for recurrent <i>Escherichia coli</i> urinary tract infection

Sander Kuiper, Anneke C. Dijkmans, Erik B. Wilms, Ingrid M. C. Kamerling, Jacobus Burggraaf, Jasper Stevens, Cees van Nieuwkoop

Journal of Antimicrobial Chemotherapy · 2020 · 15 citations · 30 references

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Abstract

Oral fosfomycin at 3 g every 72 h provides plasma and urine concentrations of fosfomycin above the MIC for E. coli. This pharmacokinetic model can be used to develop optimal dosing regimens of fosfomycin in patients with UTI.

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