Concepedia

Linear Transit Compartment Models

Linear Transit Compartment Models is a mathematical modeling framework within pharmacokinetics that, as a subclass of compartmental models, uses linear differential equations to describe the sequential and deterministic transfer of substances through a series of interconnected physiological compartments.

11

Publications

998

Citations

43

Authors

25

Institutions

Publications per year

2017–2026

2

Parents

Publications

11

Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies

Radojka M. Savić, Daniël M. Jonker, Thomas Kerbusch et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2007 · 497 citations

, , +16

Transit Compartments versus Gamma Distribution Function To Model Signal Transduction Processes in Pharmacodynamics

Yu‐Nien Sun, W J Jusko · Journal of Pharmaceutical Sciences · 1998 · 161 citations

, , +16

Pharmacodynamic modeling of chemotherapeutic effects: Application of a transit compartment model to characterize methotrexate effects in vitro

Evelyn D. Lobo, Joseph P. Balthasar · AAPS PharmSci · 2002 · 126 citations · Full text

, , +16

Evaluation of the GastroPlus™ Advanced Compartmental and Transit (ACAT) Model in Early Discovery

Nathalie Gobeau, Rowan Stringer, Stefan Buck et al. · Pharmaceutical Research · 2016 · 64 citations

, , +9

Interpretation of transit compartments pharmacodynamic models as lifespan based indirect response models

Wojciech Krzyżański · Journal of Pharmacokinetics and Pharmacodynamics · 2010 · 47 citations · Full text

, , +14

1–5 of 11

Authors

43

  1. IM
    Ingrid M. C. Kamerling

    Centre for Human Drug Research, Netherlands

    2 publications · 32 citations

    2

    h-index

  2. JB
    Jacobus Burggraaf

    Centre for Human Drug Research, Netherlands

    2 publications · 32 citations

    2

    h-index

  3. JS
    Jasper Stevens

    Centre for Human Drug Research, Netherlands

    2 publications · 32 citations

    2

    h-index

  4. MO
    Mats O. Karlsson

    Uppsala University, Sweden

    2 publications · 512 citations

    2

    h-index

  5. LK
    Laura Kervezee

    Leiden University Medical Center, Netherlands

    1 publications · 16 citations

    1

    h-index

1–5 of 43

Institutions

25

  1. University at Buffalo, State University of New York

    Buffalo, United States

    4 h-index

    8 publications

    666 citations

  2. Centre for Human Drug Research

    Leiden, The Netherlands

    2 h-index

    8 publications

    128 citations

  3. Leiden University Medical Center

    Leiden, The Netherlands

    2 h-index

    5 publications

    80 citations

  4. Uppsala University

    Uppsala, Sweden

    2 h-index

    7 publications

    2K citations

  5. University of Groningen

    Groningen, The Netherlands

    1 h-index

    1 publications

    16 citations

  6. University Medical Center Groningen

    Groningen, The Netherlands

    1 h-index

    1 publications

    16 citations

  7. Novartis Institutes for BioMedical Research

    Basel, Switzerland

    1 h-index

    4 publications

    256 citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    1 h-index

    1 publications

    15 citations

1–8 of 25

Venues

  1. 3

    h-index

  2. 1

    h-index

  3. Journal of Antimicrobial Chemotherapy

    JAC · 1 publications · 16 citations

    1

    h-index

  4. Clinical Pharmacokinetics

    1 publications · 15 citations

    1

    h-index

  5. AAPS PharmSci

    1 publications · 126 citations

    1

    h-index

1–5