Concepedia

Transit Compartment Modeling

Transit Compartment Modeling is a compartmental modeling framework in pharmacokinetics and pharmacodynamics that represents temporal delays or maturation processes by chaining a series of identical, hypothetical transit compartments through which material or signal flows sequentially according to first-order kinetics.

11

Publications

1.2K

Citations

26

Authors

17

Institutions

Publications per year

2017–2026

2

Variants

Transit Compartment Models

Parents

Children

Publications

11

Implementation of a transit compartment model for describing drug absorption in pharmacokinetic studies

Radojka M. Savić, Daniël M. Jonker, Thomas Kerbusch et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2007 · 497 citations

, , +16

Compartmental transit and dispersion model analysis of small intestinal transit flow in humans

Lawrence X. Yu, John R. Crison, Gordon L. Amidon · International Journal of Pharmaceutics · 1996 · 232 citations

, , +16

Transit Compartments versus Gamma Distribution Function To Model Signal Transduction Processes in Pharmacodynamics

Yu‐Nien Sun, W J Jusko · Journal of Pharmaceutical Sciences · 1998 · 161 citations

, , +16

Evaluation of the GastroPlus™ Advanced Compartmental and Transit (ACAT) Model in Early Discovery

Nathalie Gobeau, Rowan Stringer, Stefan Buck et al. · Pharmaceutical Research · 2016 · 64 citations

, , +9

Interpretation of transit compartments pharmacodynamic models as lifespan based indirect response models

Wojciech Krzyżański · Journal of Pharmacokinetics and Pharmacodynamics · 2010 · 47 citations · Full text

, , +14

1–5 of 11

Authors

26

  1. TE
    Thomas E. Wehrly

    Texas A&M University, United States

    1 publications · 41 citations

    1

    h-index

  2. AM
    A. Martı́n del Rey

    Universidad de Salamanca, Spain

    1 publications · 35 citations

    1

    h-index

  3. AV
    Andrew Vick

    Eli Lilly (United States), United States

    1 publications · 25 citations

    1

    h-index

  4. YS
    Yu‐Nien Sun

    University at Buffalo, State University of New York, United States

    1 publications · 161 citations

    1

    h-index

  5. AB
    Alison Boeckmann

    Dongshin University, South Korea

    1 publications · 25 citations

    1

    h-index

1–5 of 26

Institutions

17

  1. University at Buffalo, State University of New York

    Buffalo, United States

    2 h-index

    3 publications

    369 citations

  2. Therapeutics Systems Research Laboratories (United States)

    Ann Arbor, United States

    1 h-index

    1 publications

    232 citations

  3. Merck KGaA, Darmstadt (Germany)

    Darmstadt, Germany

    1 h-index

    1 publications

    11 citations

  4. University of Michigan

    Ann Arbor, United States

    1 h-index

    2 publications

    464 citations

  5. Novartis (Switzerland)

    Basel, Switzerland

    1 h-index

    4 publications

    256 citations

  6. Dongshin University

    Naju, South Korea

    1 h-index

    1 publications

    25 citations

  7. Universidad de Salamanca

    Salamanca, Spain

    1 h-index

    2 publications

    70 citations

  8. Université de Montréal

    Montreal, Canada

    1 h-index

    1 publications

    19 citations

1–8 of 17

Venues

  1. 3

    h-index

  2. Pharmaceutical Research

    1 publications · 64 citations

    1

    h-index

  3. The AAPS Journal

    AAPSJ · 1 publications · 11 citations

    1

    h-index

  4. Cell Proliferation

    1 publications · 29 citations

    1

    h-index

  5. International Journal of Pharmaceutics

    1 publications · 232 citations

    1

    h-index

1–5