Automated patch clamp in drug discovery: major breakthroughs and innovation in the last decade

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Muscle Physiology, Muscle Function, Single-channel Currents +11

Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

Yasuteru Sakurai, Andrey A. Kolokoltsov, Cheng‐Chang Chen et al. · Science · 2015 · 542 citations

Disease Treatment, Viral Pathogenesis, Immunology +17

Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium

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Heart Failure, Cardiac Anaesthesia, White Paper +21

High-Throughput Reclassification of SCN5A Variants

Andrew M. Glazer, Yuko Wada, Bian Li et al. · The American Journal of Human Genetics · 2020 · 149 citations · Full text

Engineering, Scn5a Variants, Computational Biology +5

Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca2+ Currents in Isolated Lysosomes

Michael Schieder, Katrin Rötzer, Andrea Brüggemann et al. · Journal of Biological Chemistry · 2010 · 141 citations · Full text

Isolated Lysosomes, Molecular Biology, Cellular Physiology +18