Genome editing using Cas9-RNA ribonucleoprotein complexes in the high-productivity marine alga Picochlorum celeri

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

John G. Doench, Nicolò Fusi, Meagan E. Sullender et al. · Nature Biotechnology · 2016 · 4.7K citations · Full text

Systems Biology, Off-target Effect, Natural Sciences +10

Culture of Marine Invertebrate Animals

R.S.V. Pullin · Biochemical Society Transactions · 1976 · 1.2K citations · Full text

Biology, Engineering, Marine Biodiversity +6

The Assimilatory Nitrate-Reducing System and its Regulation

Miguel G. Guerrero, José M. Vega, M. Losada · Annual Review of Plant Physiology · 1981 · 654 citations

Engineering, Redox Biology, Biosynthesis +16

Identification of the Carotenoid Isomerase Provides Insight into Carotenoid Biosynthesis, Prolamellar Body Formation, and Photomorphogenesis

Hyoungshin Park, Sarah S. Kreunen, Abby J. Cuttriss et al. · The Plant Cell · 2002 · 486 citations · Full text

Prolamellar Body Formation, Plant Physiology, Photorespiration +18

Lipid production in Nannochloropsis gaditana is doubled by decreasing expression of a single transcriptional regulator

Imad Ajjawi, John Verruto, Moena Aqui et al. · Nature Biotechnology · 2017 · 464 citations

Biology, Biosynthesis, Lipid Production +10