Concepedia

PINK1 phosphorylates Drp1S616 to regulate mitophagy‐independent mitochondrial dynamics

Hailong Han, Jieqiong Tan, Ruoxi Wang, Huida Wan, Yaohui He, Xinxiang Yan, Jifeng Guo, Qingtao Gao, Jie Li, Shuai Shang,

EMBO Reports · 2020 · 204 citations · 42 references

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42

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

Derek P. Narendra, Seok Min Jin, Atsushi Tanaka et al. · PLoS Biology · 2010 · 2.9K citations · Full text

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The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Michael Lazarou, Danielle A. Sliter, Lesley A. Kane et al. · Nature · 2015 · 2.7K citations

, , +13

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

Noriyuki Matsuda, Shigeto Sato, Kahori Shiba et al. · The Journal of Cell Biology · 2010 · 1.9K citations · Full text

, , +17

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

Lígia C. Gomes, Giulietta Di Benedetto, Luca Scorrano · Nature Cell Biology · 2011 · 1.7K citations · Full text

, , +12

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

Cristòfol Vives-Bauzá, Chun Hui Zhou, Yong Huang et al. · Proceedings of the National Academy of Sciences · 2009 · 1.6K citations

, , +17