ULK1 inhibition as a targeted therapeutic strategy for FLT3-ITD-mutated acute myeloid leukemia

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 6.8K citations · Full text

Mtor Regulate Autophagy, Mitophagy, Cell Autophagy +10

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.8K citations · Full text

Signal Transduction, Control Cell Growth, Cell Division +10

Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a <i>FLT3</i> Mutation

Richard M. Stone, Sumithra J. Mandrekar, Ben L. Sanford et al. · New England Journal of Medicine · 2017 · 2.1K citations · Full text

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Chang Hwa Jung, Chang Jun, Seung‐Hyun Ro et al. · Molecular Biology of the Cell · 2009 · 2K citations · Full text

Mitophagy, Leucine Deprivation, Immunology +16

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

Ryan C. Russell, Ye Tian, Hai‐Xin Yuan et al. · Nature Cell Biology · 2013 · 1.5K citations · Full text

Inflammation, Ulk1 Induces, Mitophagy +12