Concepedia

Phenformin inhibits proliferation, invasion, and angiogenesis of cholangiocarcinoma cells via AMPK-mTOR and HIF-1A pathways

Rattanaporn Jaidee, Sarinya Kongpetch, Laddawan Senggunprai, Auemduan Prawan, Upa Kukongviriyapan, Veerapol Kukongviriyapan

Naunyn-Schmiedeberg s Archives of Pharmacology · 2020 · 19 citations · 22 references

DOI

Concepts

References

22

Type 2 diabetes increases and metformin reduces total, colorectal, liver and pancreatic cancer incidences in Taiwanese: a representative population prospective cohort study of 800,000 individuals

Meei-Shyuan Lee, Chih-Cheng Hsu, Mark L. Wahlqvist et al. · BMC Cancer · 2011 · 463 citations · Full text

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mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3

Kayleigh Dodd, Jee Myung Yang, Ming Hong Shen et al. · Oncogene · 2014 · 388 citations · Full text

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Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial

Sil Kordes, Michaël Pollak, Aeilko H. Zwinderman et al. · The Lancet Oncology · 2015 · 380 citations

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The Mitochondrial Permeability Transition

Andrew P. Halestrap · 2002 · 254 citations

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Phenformin enhances the therapeutic benefit of BRAF <sup>V600E</sup> inhibition in melanoma

Ping Yuan, Koichi Ito, Rolando Pérez‐Lorenzo et al. · Proceedings of the National Academy of Sciences · 2013 · 223 citations · Full text

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