Identification and functional activity of matrix-remodeling associated 5 (MXRA5) in benign hyperplastic prostate

Abstract

Microarray analysis and integrated bioinformatics were conducted. The expression and biologic functions of MXRA5 was investigated via RT-PCR, western-blot, immunofluorescence, flow cytometry and MTT assay. Finally, genes involved in regulation of the MAPK pathway were investigated.