Concepedia

Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO <sub>3</sub> nanoformulation triggers ferroptosis in target tumor cells

Chencheng Xue, Menghuan Li, Yang Zhao, Jun Zhou, Yan Hu, Kaiyong Cai, Yanli Zhao, Shu‐Hong Yu, Zhong Luo

Science Advances · 2020 · 295 citations · 30 references

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Abstract

This study describes a ferroptosis/apoptosis-based treatment strategy via the cooperation between Fe 2+ and doxorubicin.

References

30

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

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Ferroptosis as a p53-mediated activity during tumour suppression

Le Jiang, Ning Kon, Tongyuan Li et al. · Nature · 2015 · 3.4K citations · Full text

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Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

Valerian E. Kagan, Gaowei Mao, Feng Qu et al. · Nature Chemical Biology · 2016 · 2.8K citations · Full text

, , +7

X-ray photoelectron spectroscopy: Towards reliable binding energy referencing

Grzegorz Greczyński, Lars Hultman · Progress in Materials Science · 2019 · 2.5K citations · Full text

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Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Wan Seok Yang, Katherine J. Kim, Michael M. Gaschler et al. · Proceedings of the National Academy of Sciences · 2016 · 2.3K citations · Full text

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