Concepedia

Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor–mediated chemotaxis

Esther van den Bos, Benjamin Ambrosy, Markus Horsthemke, Stefan Walbaum, Anne C. Bachg, Nina Wettschureck, Giulio Innamorati, Thomas M. Wilkie, Peter J. Hanley

Journal of Biological Chemistry · 2020 · 19 citations · 33 references

DOIFull text

Open access

Concepts

Abstract

signaling, and membrane protrusive activity is promoted by G proteins that deplete phosphatidylinositol 4,5-bisphosphate.

References

33

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Conditional gene targeting in macrophages and granulocytes using LysMcre mice

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Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

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