Bruceine D elevates Nrf2 activation to restrain Parkinson’s disease in mice through suppressing oxidative stress and inflammatory response

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

Ralf A. Linker, De-Hyung Lee, Sarah Ryan et al. · Brain · 2011 · 1.2K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

David Weismann, Karsten Hartvigsen, Nadine Lauer et al. · Nature · 2011 · 525 citations

Life Sciences, Immunology, Molecular Biology +16

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells

Lisa Pike, Amy Smift, Nicole J. Croteau et al. · Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2010 · 463 citations

Life Sciences, Biochemistry, Pharmacology +17

Inhibition of NF-κB nuclear translocation via HO-1 activation underlies α-tocopheryl succinate toxicity

Ilaria Bellezza, Arianna Tucci, Francesco Galli et al. · The Journal of Nutritional Biochemistry · 2012 · 214 citations

Life Sciences, Cell Biology, Molecular Biology +10

Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo

Jiangjiang Fan, Dong‐Mei Ren, Jinxia Wang et al. · Cell Death and Disease · 2020 · 201 citations · Full text

Life Sciences, Oncology, Pharmacology +10