Altered clearance of beta-amyloid from the cerebrospinal fluid following subchronic lead exposure in rats: Roles of RAGE and LRP1 in the choroid plexus

RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain

Rashid Deane, Shi Du Yan, Ram Kumar Submamaryan et al. · Nature Medicine · 2003 · 1.4K citations

Life Sciences, Neurobiology, Neuroscience +14

A multimodal RAGE-specific inhibitor reduces amyloid β–mediated brain disorder in a mouse model of Alzheimer disease

Rashid Deane, Itender Singh, Abhay P. Sagare et al. · Journal of Clinical Investigation · 2012 · 612 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

RAGE, LRP-1, and amyloid-beta protein in Alzheimer’s disease

John E. Donahue, Stephanie Flaherty, Conrad E. Johanson et al. · Acta Neuropathologica · 2006 · 504 citations

Life Sciences, Neurobiology, Neuroscience +14

The Fetal Basis of Amyloidogenesis: Exposure to Lead and Latent Overexpression of Amyloid Precursor Protein and β-Amyloid in the Aging Brain

Riyaz Basha, Wei Wei, Saleh A. Bakheet et al. · Journal of Neuroscience · 2005 · 347 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Longitudinal study of cerebrospinal fluid levels of tau, Aβ1–40, and Aβ1–42(43) in Alzheimer's disease: A study in Japan

Mitsuyasu Kanai, E. Matsubara, Kenji Isoe et al. · Annals of Neurology · 1998 · 342 citations

Medicine, Neurology, Neuroscience +17