Sulforaphane and iberin are potent epigenetic modulators of histone acetylation and methylation in malignant melanoma

DNA damage activates p53 through a phosphorylation–acetylation cascade

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Life Sciences, Cell Biology, Molecular Biology +13

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate

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Life Sciences, Cancer Biology, Cell Biology +8

p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage

Lin Liu, Daniel M. Scolnick, Raymond C. Trievel et al. · Molecular and Cellular Biology · 1999 · 777 citations

Life Sciences, Molecular Biology, Molecular Genetics +14

Global Histone Modifications in Breast Cancer Correlate with Tumor Phenotypes, Prognostic Factors, and Patient Outcome

Somaia Elsheikh, Andrew R. Green, Emad A. Rakha et al. · Cancer Research · 2009 · 506 citations · Full text

Medicine, Molecular Biology, Oncology +17

HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade

David Woods, Andressa L. Sodré, Alejandro Villagra et al. · Cancer Immunology Research · 2015 · 434 citations · Full text

Life Sciences, Immunology, Oncology +17