Concepedia

Targeting Inflammation, PHA-767491 Shows a Broad Spectrum in Protein Aggregation Diseases

Yu-Han Chung, Chia-Wei Lin, Hsin‐Yu Huang, Shu-Ling Chen, Hei-Jen Huang, Ying‐Chieh Sun, Guan-Chiun Lee, Guey‐Jen Lee‐Chen, Ya-Ching Chang, Hsiu Mei Hsieh‐Li

Journal of Molecular Neuroscience · 2020 · 16 citations · 37 references

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37

Atomic structures of amyloid cross-β spines reveal varied steric zippers

M.R. Sawaya, Shilpa Sambashivan, Rebecca A. Nelson et al. · Nature · 2007 · 2.3K citations

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SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein

Koichiro Nakamura · Human Molecular Genetics · 2001 · 627 citations · Full text

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Early and Progressive Accumulation of Reactive Microglia in the Huntington Disease Brain

Ellen Sapp, Kimberly B. Kegel, Neil Aronin et al. · Journal of Neuropathology & Experimental Neurology · 2001 · 540 citations · Full text

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Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

A.D. Kazantsev, Elizabeth Preisinger, Alex Dranovsky et al. · Proceedings of the National Academy of Sciences · 1999 · 455 citations

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Microglial activation in presymptomatic Huntington's disease gene carriers

Yen Tai, Nicola Pavese, Alexander Gerhard et al. · Brain · 2007 · 434 citations · Full text

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