Concepedia

Aggregation Pathways

Aggregation Pathways is a theoretical framework that specifies the sequence of conformational and intermolecular events by which misfolded or partially folded proteins assemble into ordered, often pathogenic, supramolecular structures through defined intermediate states and kinetic routes.

314

Publications

19.4K

Citations

1.4K

Authors

504

Institutions

Publications per year

2017–2026

104

Variants

Protein Aggregation Pathways

Parents

Publications

314

Molecular mechanisms of protein aggregation from global fitting of kinetic models

Georg Meisl, Julius B. Kirkegaard, Paolo Arosio et al. · Nature Protocols · 2016 · 789 citations

, , +17

p62 Is a Common Component of Cytoplasmic Inclusions in Protein Aggregation Diseases

Kurt Zatloukal, Cornelia Stumptner, Andrea Fuchsbichler et al. · American Journal Of Pathology · 2002 · 617 citations · Full text

, , +13

Aggregation as bacterial inclusion bodies does not imply inactivation of enzymes and fluorescent proteins

Elena García‐Fruitós, Núria González‐Montalbán, Montse Morell et al. · Microbial Cell Factories · 2005 · 326 citations · Full text

, , +16

Life on the edge: a link between gene expression levels and aggregation rates of human proteins

Gian Gaetano Tartaglia, Sebastian Pechmann, Christopher M. Dobson et al. · Trends in Biochemical Sciences · 2007 · 299 citations

, , +16

Quantitative and spatio‐temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageing

Juliane Winkler, Anja Seybert, Lars M. König et al. · The EMBO Journal · 2010 · 291 citations · Full text

, , +17

1–5 of 314

Authors

1.4K

  1. MH
    Mi Hee Lim

    Ulsan National Institute of Science and Technology, South Korea

    7 publications · 392 citations

    7

    h-index

  2. CM
    Christopher M. Dobson

    University of Cambridge, United Kingdom

    6 publications · 1.4K citations

    6

    h-index

  3. FC
    Fabrizio Chiti

    University of Florence, Italy

    5 publications · 232 citations

    5

    h-index

  4. GF
    Gustavo Fernández

    University of Münster, Germany

    5 publications · 228 citations

    5

    h-index

  5. BS
    Birgit Strodel

    Forschungszentrum Jülich, Germany

    5 publications · 295 citations

    5

    h-index

1–5 of 1.4K

Institutions

504

  1. University of Cambridge

    Cambridge, United Kingdom

    15 h-index

    57 publications

    9.9K citations

  2. Massachusetts Institute of Technology

    Cambridge, United States

    8 h-index

    21 publications

    1.5K citations

  3. University of Leeds

    Leeds, United Kingdom

    7 h-index

    24 publications

    1.8K citations

  4. Ulsan National Institute of Science and Technology

    Ulsan, South Korea

    7 h-index

    25 publications

    1.3K citations

  5. Heinrich Heine University Düsseldorf

    Düsseldorf, Germany

    6 h-index

    9 publications

    476 citations

  6. Universitat Autònoma de Barcelona

    Cerdanyola del Vallès, Spain

    6 h-index

    20 publications

    2.9K citations

  7. University of Münster

    Münster, Germany

    6 h-index

    18 publications

    718 citations

  8. Amgen (United States)

    Thousand Oaks, United States

    6 h-index

    19 publications

    1.5K citations

1–8 of 504

Venues

  1. Journal of Biological Chemistry

    JBC · 15 publications · 1.1K citations

    15

    h-index

  2. Biochemistry

    16 publications · 806 citations

    14

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 13 publications · 1.5K citations

    13

    h-index

  4. Angewandte Chemie International Edition

    9 publications · 832 citations

    9

    h-index

  5. Journal of Molecular Biology

    JMB · 8 publications · 589 citations

    8

    h-index

1–5