Rosacea Is Characterized by a Profoundly Diminished Skin Barrier

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

Gabriela Bindea, Bernhard Mlecnik, Hubert Hackl et al. · Bioinformatics · 2009 · 6.5K citations · Full text

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Alan D. Irvine, Ana Terron-Kwiatkowski, Yiwei Zhao et al. · Nature Genetics · 2006 · 2.9K citations

Major Predisposing Factor, Common Loss-of-function Variants, Atopic Dermatitis +8

Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

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Inflammation, Medicine, Cutaneous Biology +7

Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells

Monica Rimoldi, Marcello Chieppa, Valentina Salucci et al. · Nature Immunology · 2005 · 797 citations

Inflammation, Chronic Inflammatory Diseases, Autoimmune Disease +13

Tight junction defects in patients with atopic dermatitis

Anna De Benedetto, Nicholas Rafaels, Laura Y. McGirt et al. · Journal of Allergy and Clinical Immunology · 2010 · 713 citations

Atopic Dermatitis, Tight Junction Defects, Skin Allergy +2