Concepedia

Epigenetically modifying the Foxp3 locus for generation of stable antigen-specific Tregs as cellular therapeutics

Shuqiu Chen, Lei Zhang, Yuanlin Ying, Yixuan Wang, Preston R. Arnold, Guangchuan Wang, Junhui Li, R. Mark Ghobrial, Wenhao Chen, Xiang Xiao,

American Journal of Transplantation · 2020 · 22 citations · 25 references

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25

A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

Hervé Groux, Anne O’Garra, Mike Bigler et al. · Nature · 1997 · 3.6K citations

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

Craig L. Bennett, Jacinda R. Christie, Fred Ramsdell et al. · Nature Genetics · 2001 · 3.4K citations

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Jeong Kim, Jeffrey P. Rasmussen, Alexander Y. Rudensky · Nature Immunology · 2006 · 1.8K citations

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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

Xuyu Zhou, Samantha L. Bailey-Bucktrout, Lukas T. Jeker et al. · Nature Immunology · 2009 · 1.3K citations · Full text

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Epigenetic Control of the foxp3 Locus in Regulatory T Cells

Stefan Floess, Jennifer Freyer, Christiane Siewert et al. · PLoS Biology · 2007 · 1.2K citations · Full text

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