CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

Weihong Liu, Amy Putnam, Xuyu Zhou, +11

The Journal of Experimental Medicine

T-regulatory CellImmune RegulationImmunologyRegulatory T CellsCd4 T Cell Responses +16

Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

Xuyu Zhou, Samantha L. Bailey-Bucktrout, Lukas T. Jeker, +6

Nature Immunology

Adaptive Immune SystemT-regulatory CellTranscription Factor Foxp3ImmunologyCell Death +6

Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity

Xuyu Zhou, Lukas T. Jeker, Brian T. Fife, +4

The Journal of Experimental Medicine

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

James M. Gardner, Jason DeVoss, Rachel S. Friedman, +8

Science

Autoimmune DiseaseLymphocyte DevelopmentMedicineImmunologyDeletional Tolerance Mediated +12

Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response

Samantha L. Bailey-Bucktrout, Marc Martínez‐Llordella, Xuyu Zhou, +5

Immunity

InflammationAllergyAutoimmune DiseaseInflammatory Autoimmune ResponseT-regulatory Cell +8

B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen

Hong Sheng, Zhimin Zhang, Hongtao Liu, +11

Immunity

VaccinationVirus-derived Nanoparticle AntigenAdaptive Immune SystemHumoral ResponseImmunology +11

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

Marc Beyer, Yasser Thabet, Roman‐Ulrich Müller, +31

Nature Immunology

Transcriptional RegulationEffector DifferentiationSignal TransductionCell RegulationGenetics +11

In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation

Karen Earle, Qizhi Tang, Xuyu Zhou, +4

Clinical Immunology

T-regulatory CellImmunologyRegulatory T CellsAutoimmunitySelf-tolerance +5

Reciprocal Expression of IL-35 and IL-10 Defines Two Distinct Effector Treg Subsets that Are Required for Maintenance of Immune Tolerance

Xundong Wei, Jianhua Zhang, Qianchong Gu, +4

Cell Reports

Il-10 Defines TwoImmune ToleranceLymphocyte DevelopmentT-regulatory CellImmunology +18

Non-CD28 Costimulatory Molecules Present in T Cell Rafts Induce T Cell Costimulation by Enhancing the Association of TCR with Rafts

Yumi Yashiro–Ohtani, Xuyu Zhou, Kazuhito Toyo‐oka, +6

The Journal of Immunology