Concepedia

<p>Caspase-3 Promotes Diabetic Kidney Disease Through Gasdermin E-Mediated Progression to Secondary Necrosis During Apoptosis</p>

Wen Si, Zhaohua Wang, Congxiao Zhang, Ying Yang, Qiuling Fan

Diabetes Metabolic Syndrome and Obesity · 2020 · 45 citations · 24 references

DOIFull text

Open access

Abstract

These data suggest GSDME-dependent secondary necrosis plays a crucial role in renal injury, and provides a new insight into the pathogenesis of DKD and a promising target for its treatment.

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