Dihydroartemisinin inhibits the proliferation of IgAN mesangial cells through the mTOR signaling pathway

High-level semi-synthetic production of the potent antimalarial artemisinin

Christopher J. Paddon, Patrick J. Westfall, Douglas J. Pitera et al. · Nature · 2013 · 2.1K citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells

Renyu Lin, Ziheng Zhang, Lingfeng Chen et al. · Cancer Letters · 2016 · 303 citations

Life Sciences, Cell Biology, Oncology +8

Identification of the Transferrin Receptor as a Novel Immunoglobulin (Ig)a1 Receptor and Its Enhanced Expression on Mesangial Cells in Iga Nephropathy

Ivan Cruz Moura, Miguel N. Centelles, Michelle Arcos‐Fajardo et al. · The Journal of Experimental Medicine · 2001 · 283 citations · Full text

Life Sciences, Immunology, Pathology +17

Dihydroartemisinin inactivates NF-κB and potentiates the anti-tumor effect of gemcitabine on pancreatic cancer both in vitro and in vivo

Shuangjia Wang, Yue Gao, Hua Chen et al. · Cancer Letters · 2010 · 165 citations

Medicine, Oncology, Pharmacology +11

Individuals of Pacific Asian origin with IgA nephropathy have an increased risk of progression to end-stage renal disease

Sean J. Barbour, Daniel C. Cattran, S. Joseph Kim et al. · Kidney International · 2013 · 159 citations · Full text

Medicine, Internal Medicine, Nephrology +10